Pfizer Shares Gain Amid Reports of Deal with the US Government

Pfizer Inc. (PFE) shares rose 3.30% to $24.64 as of 10:38 AM EDT on September 30, 2025, following reports that President Donald Trump will announce a drug-pricing agreement with the pharmaceutical giant. The deal, part of the White House’s “Most Favored Nation” initiative, would potentially see Pfizer voluntarily sell medications through Medicaid at reduced prices linked to the lowest costs paid by wealthy nations.

This development comes as the administration intensifies pressure on pharmaceutical companies to lower drug prices for American consumers, with Monday marking the deadline for voluntary agreements.

USG Pfizer Drug-Pricing Deal: Context and Implications for the Firm

The forthcoming agreement represents a significant development in the Trump administration’s ongoing effort to reduce prescription drug costs for Americans. According to reports from The Washington Post, the deal involves Pfizer voluntarily offering its medications through Medicaid at prices aligned with those paid by wealthier nations abroad.

President Trump signed an executive order in May 2025 laying out this “Most Favored Nation” pricing initiative, and administration officials have since been negotiating with pharmaceutical companies to secure voluntary commitments before the September 29 deadline.

The pharmaceutical industry has been under mounting pressure from the White House through a combination of tariff threats and new regulatory initiatives. The Centers for Medicare and Medicaid Services is reportedly developing several pilot programs that could impose additional drug-pricing controls within the Medicare program.

In response, the industry’s main lobbying group, the Pharmaceutical Research and Manufacturers of America, announced voluntary measures on Monday, including a new website to help Americans comparison-shop for lower-priced medications.

Trump has repeatedly argued that the United States subsidizes drug costs for the rest of the world, stating last week, “We pay much higher for drugs than the rest of the world. We subsidize the rest of the world. We’re not doing that anymore.”

Join our Telegram group and never miss a breaking digital asset story.

Pfizer Shares Edge Upwards Amid Deal News

Pfizer shares traded at $24.64 with a market capitalization of $140.065 billion as of Tuesday morning, representing a gain of $0.79 or 3.30% from the previous close of $23.85. The stock has struggled over longer time periods, down 8.90% over the past year and showing a steep 33.63% decline over three years, significantly underperforming the S&P 500’s 15.37% and 85.42% gains over the same periods respectively. Trading volume reached 39.3 million shares, slightly below the average volume of 43.3 million.

From a valuation perspective, Pfizer presents a mixed picture with a trailing P/E ratio of 12.97 and a more attractive forward P/E of 7.61, suggesting analyst expectations for improved earnings. The company offers a robust dividend yield of 7.24% with a forward dividend of $1.72 per share. Analyst consensus points to a price target of $28.90, representing potential upside of approximately 17% from current levels.

The company reported trailing twelve-month revenue of $63.83 billion and net income of $10.73 billion, with a profit margin of 16.84% and levered free cash flow of $16.02 billion. With the next earnings report scheduled for November 4, 2025, investors will be closely watching for management commentary on the drug-pricing agreement and its potential impact on future revenue and profitability.

Disclaimer: The author does not hold or have a position in any securities discussed in the article. All stock prices were quoted at the time of writing.